生物信息学 · katucharts.js/bio

火山图

type: 'volcano'

火山图——折叠变化(x)与统计显著性(−log10 p值,y)。点按显著性阈值着色:上调、下调、无显著性。

编辑右侧的JSON并按Run(或⌘/Ctrl + Enter)——数据、标题、类别和颜色全部实时更新。

实时
火山图
编辑 · JSON

数据格式

{ x: log2FC, y: -log10pval, name?: geneName }

数据结构

传入图表的 JSON——可直接放进你的 series。

data: [
  { x: 2.5, y: 10.3, name: 'BRCA1' },
  { x: -1.8, y: 4.2, name: 'TP53' },
  { x: 0.8, y: 8.1, name: 'PTEN' }
]

示例

import KatuCharts from 'katucharts.js';
import 'katucharts.js/bio';

KatuCharts.chart('container', {
  series: [{
    type: 'volcano',
    data: [{ x: 2.5, y: 10.3, name: 'BRCA1' }, { x: -1.8, y: 4.2, name: 'TP53' }],
    foldChangeThreshold: 1,
    pValueThreshold: 0.01
  }]
});

类型特定选项

选项描述
thresholds{ foldChange、pValue }分类截点。
colors{ upregulated、downregulated、nonsignificant }。
labelTopN标记最显著的前N个基因。

变体

标注显著基因

用 labelTopN 标注最显著的数据点。

KatuCharts.chart('container', {
  series: [{
    type: 'volcano',
    data: genes,
    foldChangeThreshold: 1,
    pValueThreshold: 0.01,
    labelTopN: 8
  }]
});

Common errors

Why does my 火山图 chart render as a line chart?
The chart type was not registered. KatuCharts logs "KatuCharts: unknown series type "<type>", falling back to line" and draws a line chart rather than throwing. Import the module the type belongs to — for example `import 'katucharts.js/bio';` — before creating the chart.
Why do I get "Cannot read properties of null (reading 'appendChild')"?
The container element does not exist when the chart is created. Create the chart after the element is in the DOM: in React that means inside useEffect, not during render.
Why is the chart rendering with zero height?
The container has no height. A div with no content collapses to zero. Give it a height in CSS, or pass `chart: { height: 400 }` in the options.

FAQ

How do I create a 火山图 chart in JavaScript?
Install with `npm install katucharts.js`, import the module with `import 'katucharts.js/bio';`, then call KatuCharts.chart(container, { chart: { type: 'volcano' }, series: [...] }).
What data does the volcano plot expect?
Points that are already transformed: { x: log2 fold change, y: −log10(p), name }. Compute −log10 of your p-values (or adjusted p-values) before passing them in; the series does not read DESeq2, edgeR or limma result tables directly.
How are points classified as up-regulated, down-regulated or not significant?
With foldChangeThreshold (default 1) and pValueThreshold (default 0.05) on the series. Dashed threshold lines are drawn at ±foldChangeThreshold and at −log10(pValueThreshold), and the three groups are coloured with upColor, downColor and nsColor.
How do I label the most significant genes?
Set labelTopN on the series, for example labelTopN: 8. Labels use each point's name.
Why does my 火山图 chart render as a line chart?
The chart type was not registered. KatuCharts logs "KatuCharts: unknown series type "<type>", falling back to line" and draws a line chart rather than throwing. Import the module the type belongs to — for example `import 'katucharts.js/bio';` — before creating the chart.
Why do I get "Cannot read properties of null (reading 'appendChild')"?
The container element does not exist when the chart is created. Create the chart after the element is in the DOM: in React that means inside useEffect, not during render.
通用选项(color、visible、marker、dataLabels、animation、events、zones…)适用于每个类型——请参阅配置→series。在图库中查看其渲染。